Reperfusion therapy of ischemic stroke

Reperfusion therapy in the acute management of ischemic stroke.

Reperfusion, or restoration of blood flow, is an effective means of reducing disability in the setting of acute stroke. Reperfusion therapies, such as intravenous thrombolysis or endovascular and interventional procedures, fit within the existing stroke system of care. There are currently 4 devices cleared by the Food and Drug Administration for recanalization of arterial occlusion in patients ...

Reperfusion Therapy in Very Elderly with Acute Ischemic Stroke

Background: Very elderly (age ≥80yo) individuals account for about one-third of all stroke admissions with mixed literature demonstrating relative poor stroke outcomes. With overwhelming recent evidence supporting the use of intra-arterial thrombectomy in addition to IV thrombolysis for large-vessel occlusive stroke, we conducted a pool analysis to assess long-term functional outcome following ...

Recanalization and reperfusion in acute ischemic stroke

Revascularization remains the most intuitive strategy to reverse ischemic injury associated with arterial occlusion in acute stroke. Revascularization may lead to opening of an occluded artery, or recanalization, yet restoration of downstream flow, or reperfusion, may not ensue. Revascularization strategies and novel devices continue to broaden options for the treatment of acute stroke, but it ...

Acute ischemic stroke: time, penumbra, and reperfusion.

Oxygen therapy in ischemic stroke.

To the Editor: Previous studies of therapeutic oxygen in stroke have had conflicting results, and the latest study by Rusyniak et al1 seems to suggest that hyperbaric oxygen therapy (HBO) is harmful in ischemic stroke. The authors have already discussed how several inadequacies in trial design might explain their negative results. We wish to draw attention to additional features in their study ...